#triple-agonist

Retatrutide — Triple GLP-1/GIP/Glucagon Agonist Research Review

Retatrutide is the first triple agonist of GLP-1, GIP, and glucagon receptors to enter major incretin research. This review walks through its mechanism — what each receptor arm contributes, why glucagon-receptor activation matters, and how the triple-receptor profile compares to dual-incretin compounds.